Product Overview

Barbituric acid
 ReagentPlus®, 99%
Synonym(s):
Malonylurea, 2,4,6-Trihydroxypyrimidine
Empirical Formula (Hill Notation):
C4H4N2O3
CAS Number:
67-52-7
Molecular Weight:
128.09
Beilstein:
120502

Barbituric acid is a useful acid for organic and drug syntheses. Its dihydrate form can be synthesized from barbituric acid via crystallization from aqueous solution. Crystal structure of barbituric acid (in tautomeric form) has been investigated by a three dimensional fourier transform method. Its enol crystal form has been reported to be thermodynamically stable.

Application

Barbituric acid (BA) may be used in the preparation of the corresponding hemiaminals, via chemoselective reduction in the presence of SmI₂/H₂O reagent. It may be used in the preparation of BA- modified conjugated carbon nitride nanosheets.

It may be used to synthesize:

• 5-ylidenebarbituric acid derivatives via Knoevenagel condensation with aromatic and α,β-conjugated aromatic aldehydes
• 5-diaminomethylenebarbiturates by reacting with substituted carbodiimides

Package Size: 100 G