Y-27632 dihydrochloride ,5 MG

Synonym(s): (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-Pyridyl)cyclohexanecarboxamide dihydrochloride

Empirical Formula: C₁₄H₂₁N₃O -+ 2HCl

Linear Formula: C₁₄H₂₁N₃O -+ 2HCl

Formula Weight: 320.26

MDL Number: MFCD03490488

Purity: ≥98% (HPLC)

Storage: 2-8°C

Y-27632 dihydrochloride is an effective bronchodilator and improves lung resistance (RL) induced by antigen and acetylcholine. Y-27632 controls neutrophil migration and lung edema and maybe a potential drug for treating acute lung injury.

Application

Y-27632 dihydrochloride has been used:

• as a medium supplement in pancreatic ductal adenocarcinoma organoid culture
• in the inhibition of Ras homolog gene family (Rho) kinase in mouse embryonic stem cells
• in the inhibition of Rho-associated protein kinase (ROCK) in human embryonic stem cells and human-induced pluripotent stem cells (iPSCs)

Packaging

 5 mg in a glass bottle