Ammonium Hydrogen carbonateis a commonly used reagent for industrial and research procedures. Ammonium bicarbonate is volatile in solution and releases ammonia and CO₂. This property makes ammonium bicarbonate a good buffer for such applications as lyophilization and matrix-assisted laser desorption. Ammonium bicarbonate is also utilized for the in-gel digestion of proteins by trypsin and in the MALDI mass spectrometric analysis of proteins.

Ammonium bicarbonate