Acetylcholine Chloride 98+% (25GM)

Acetylcholine Chloride 98+% (25GM), Alfa Aesar, L02168.14 - Alfa Aesar

Acetylcholine chloride, 98+%

MDL

MFCD00011698

EINECS

200-468-8

Chemical Properties

Formula

CH₃CO₂CH₂CH₂N(CH₃)₃Cl

Formula Weight

181.66

Melting point

149-152°

Storage & Sensitivity

Keep Cold. Very Hygroscopic. Store under Argon.

Solubility

Soluble in water (600 g/L at 20°C), alcohol, DMSO (36 mg/ml at 25°C), and ethanol (36 mg/ml at 25°C). Insoluble in ether.

Applications

Acetylcholine chloride acts as an endogenous neurotransmitter at cholinergic synapses. The compound has been shown to have ophthalmological uses and can be broken down quickly by choliesterases. Acetylcholine influences many basic cells functions, such as mitosis, cell differentiation, cytoskeletal organization, and cell to cell contact, among other functions. It reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis.The cholinergicanti-infl ammatory mechanism is probably mediated by the interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.

Notes

Store away from moisture. Store under dry inert gas. Incompatible with heat, oxidizing agents.

GHS Hazard and Precautionary Statements

Hazard Statements: H303-H315-H319-H335

May be harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands, and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. Take off contaminated clothing and wash it before reuse. Store in a well-ventilated place. Keep the container tightly closed. Dispose of contents/ container to an approved waste disposal plant